哈佛医学院以及美国德州圣安东尼奥研究中心招聘信息

哈佛大学医学院Andrew Siedlecki课题组招聘访问学者、访问学生及博士后研究人员

Andrew Siedlecki MD, 

Associate Physician, Renal division, Brigham and Women’s Hospital.

Instructor, Medicine, Harvard Medical School.

Laboratory address: 

Harvard Institute of Medicine, 77 Ave louis pasteur, Boston, MA. 

Research Narrative:

The kidney is one of the most vascular organs in the human body.  Our laboratory is seeking to understand the mechanisms of vascular injury in the kidney and offer solutions to accelerate the repair process.  Our latest work analyzes the regenerative capacity of cells found in the renal artery of people at risk for kidney disease.  Cultivation of such cells offers a potential therapy to patients during a future period of declining renal function .

Selected publications:

1.Postalcioglu M, Kaze AD, Byun BC, Siedlecki A, Tullius SG, Milford EL, Paik JM, Abdi R. Association of Cold Ischemia Time With Acute Renal Transplant Rejection. Transplantation. 2018 Jul; 102(7):1188-1194. PMID: 29346257.View in: PubMed

2.Pang P, Abbott M, Abdi M, Fucci QA, Chauhan N, Mistri M, Proctor B, Chin M, Wang B, Yin W, Lu TS, Halim A, Lim K, Handy DE, Loscalzo J, Siedlecki AM. Pre-clinical model of severe glutathione peroxidase-3 deficiency and chronic kidney disease results in coronary artery thrombosis and depressed left ventricular function. Nephrol Dial Transplant. 2018 Jun 01; 33(6):923-934. PMID: 29244159. View in: PubMed

3.Chin MS, Steigner M, Yin W, Kwong RY, Siedlecki AM. Intraluminal Assessment of Coronary Arteries With Ferumoxytol-Enhanced Magnetic Resonance Angiography. JACC Cardiovasc Imaging. 2018 Mar; 11(3):505-508. PMID: 29248659. View in: PubMed

4.Reddy YN, Siedlecki AM, Francis JM. Breaking down the complement system: a review and update on novel therapies. Curr Opin Nephrol Hypertens. 2017 03; 26(2):123-128. PMID: 27977428. View in: PubMed

5.Pang P, Abbott M, Chang SL, Abdi M, Chauhan N, Mistri M, Ghofrani J, Fucci QA, Walker C, Leonardi C, Grady S, Halim A, Hoffman R, Lu T, Cao H, Tullius SG, Malek S, Kumar S, Steele G, Kibel A, Freedman BS, Waikar SS, Siedlecki AM. Human vascular progenitor cells derived from renal arteries are endothelial-like and assist in the repair of injured renal capillary networks. Kidney Int. 2017 01; 91(1):129-143. PMID: 27692806. View in: PubMed

6.Mukundan S, Steigner ML, Hsiao LL, Malek SK, Tullius SG, Chin MS, Siedlecki AM. Ferumoxytol-Enhanced Magnetic Resonance Imaging in Late-Stage CKD. Am J Kidney Dis. 2016 Jun; 67(6):984-8. PMID: 26786296; PMCID: PMC4877283 [Available on 06/01/17]. View in: PubMed, PubMed Central

7.Freedman BS, Brooks CR, Lam AQ, Fu H, Morizane R, Agrawal V, Saad AF, Li MK, Hughes MR, Werff RV, Peters DT, Lu J, Baccei A, Siedlecki AM, Valerius MT, Musunuru K, McNagny KM, Steinman TI, Zhou J, Lerou PH, Bonventre JV. Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids. Nat Commun. 2015 Oct 23; 6:8715. PMID: 26493500; PMCID: PMC4620584. View in: PubMed, PubMed Central

等数十篇论文。

Positions:

Self-funded visiting students, Self-funded postdoctoral research fellows, Visiting professors: Applicants who are interested please send the CV to Dr. Siedlecki. Applicants with PhD degree(or later-year PhD student) on relevant topics and CSC financial support will be preferentially considered.

美国德州圣安东尼奥医学研究中心意招聘博士后，主要是糖尿病以及脂肪肝研究方向

Dr Zang, MD, Ph.D. 

Barshop Institute for Longevity and Aging Studies

Department of Molecular Medicine,

University of Texas Health Science Center at San Antonio （UTHSCSA）

Zang Lab主要关注糖尿病和脂肪肝的发病机制及药物和分子治疗。The ongoing research focuses on the nutrient regulation of glucose and lipid metabolism and energy balance as well as the identification of new therapeutic mechanisms for fatty liver disease, diabetes and aging-related metabolic disease (Li Y, et al. Cell Metabolism, 2011; Gastroenterology, 2014; Luo T, et al. Diabetes, 2016； Chen H, et al, Hepatology, 2018). 在细胞和knockout小鼠模型上进行机制研究以及临床样品中验证。

合适的申请人需要具备下列背景之一：

1）分子细胞生物学，2）生物化学；  3）动物模型建立； 4）免疫组化等相关技术。

目前需要招收博士后一至两名，同时也招收国内高校，科研单位及医院系统相关专业的访问研究生（GPA优秀的本科生也将予以优先考虑），联合培养研究生，访问学者和临床医生。

如有其他需求，也可联系京华医学，京华医学主要专注于医学留学、医师海外进修项目、海外医学专家派遣、医学会议专家派遣、公务考察学习等项目，旨在为广大医疗工作者提供优质的服务。